A set of reference sequences for the hepatitis C genotypes 4d, 4f, and 4k covering the full open reading frame.

ABSTRACT: Infection with genotype 4 of the Hepatitis C virus is common in Africa and the Mediterranean area, but has also been found at increasing frequencies in injection drug users in Europe and North America. Full length viral sequences to characterize viral diversity and structure have recently become available mostly for subtype 4a, and studies in Egypt and Saudi Arabia, where high proportions of subtype 4a infected patients exist, have begun to establish optimized treatment regimens. However knowledge about other subtype variants of genotype 4 present in less developed African states is lacking. In this study the full coding region from so far poorly characterized variants of HCV genotype 4 was amplified and sequenced using a long range PCR technique. Sequences were analyzed with respect to ph

SUBMITTER: Kuntzen T 

PROVIDER: S-EPMC2818806 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature