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ABSTRACT: Objective
To compare the effects and tolerability of omeprazole and cisapride with that of placebo for control of heartburn in primary care patients.Design
Randomised, double blind, placebo controlled study.Setting
65 primary care practices in Norway.Participants
483 untreated patients with complaints of heartburn >/=3 days a week, with at most grade 1 reflux oesophagitis.Interventions
Omeprazole 20 mg once daily, cisapride 20 mg twice daily, or placebo for 8 weeks.Main outcome measures
Adequate control of heartburn, defined as ResultsIn the all patients treated analysis, adequate control of heartburn was achieved in 71% of patients taking omepra
SUBMITTER: Hatlebakk JG
PROVIDER: S-EPMC28208 | biostudies-literature | 1999 Aug
REPOSITORIES: biostudies-literature