Population dynamics of Neisseria gonorrhoeae in Shanghai, China: a comparative study.

ABSTRACT:

Background

Gonorrhea is a major sexually transmitted disease (STD) in many countries worldwide. The emergence of fluoroquinolone resistance has complicated efforts to control and treat this disease. We report the first study of the evolutionary processes acting on transmission dynamics of a resistant gonococcal population from Shanghai, China. We compare these findings with our previous study of the evolution of a fluoroquinolone sensitive gonococcal population from Baltimore, MD.

Methods

Ninety six gonococcal samples were collected from male patients in Shanghai, China. All samples were fluoroquinolone resistant. Seven MLST housekeeping genes, two fluoroquinolone resistance genes (gyrA and parC) and the porB gene were sequenced and subjected to population genetic and evolut

SUBMITTER: Tazi L 

PROVIDER: S-EPMC2822776 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature