Molecular characterization of two hantavirus strains from different rattus species in Singapore.

ABSTRACT:

Background

Hantaviruses cause human disease in endemic regions around the world. Outbreaks of hantaviral diseases have been associated with changes in rodent population density and adaptation to human settlements leading to their proliferation in close proximity to human dwellings. In a parallel study initiated to determine the prevalence of pathogens in Singapore's wild rodent population, 1206 rodents were trapped and screened. The findings established a hantavirus seroprevalence of 34%. This paper describes the molecular characterization of hantaviruses from Rattus norvegicus and Rattus tanezumi, the predominant rodents caught in urban Singapore.

Methodology

Pan-hanta RT-PCR performed on samples of Rattus norvegicus and Rattus tanezumi indicated that 27 (2.24%) of the anim

SUBMITTER: Johansson P 

PROVIDER: S-EPMC2823670 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature