An insight into the sialotranscriptome of the West Nile mosquito vector, Culex tarsalis.

ABSTRACT:

Background

Saliva of adult female mosquitoes help sugar and blood feeding by providing enzymes and polypeptides that help sugar digestion, control microbial growth and counteract their vertebrate host hemostasis and inflammation. Mosquito saliva also potentiates the transmission of vector borne pathogens, including arboviruses. Culex tarsalis is a bird feeding mosquito vector of West Nile Virus closely related to C. quinquefasciatus, a mosquito relatively recently adapted to feed on humans, and the only mosquito of the genus Culex to have its sialotranscriptome so far described.

Results

A total of 1,753 clones randomly selected from an adult female C. tarsalis salivary glands (SG) cDNA library were sequenced and used to assemble a database that yielded 809 clusters of relate

SUBMITTER: Calvo E 

PROVIDER: S-EPMC2823692 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature