The establishment of the GENEQOL consortium to investigate the genetic disposition of patient-reported quality-of-life outcomes.

ABSTRACT: To our knowledge, no comprehensive, interdisciplinary initiatives have been taken to examine the role of genetic variants on patient-reported quality-of-life outcomes. The overall objective of this paper is to describe the establishment of an international and interdisciplinary consortium, the GENEQOL Consortium, which intends to investigate the genetic disposition of patient-reported quality-of-life outcomes. We have identified five primary patient-reported quality-of-life outcomes as initial targets: negative psychological affect, positive psychological affect, self-rated physical health, pain, and fatigue. The first tangible objective of the GENEQOL Consortium is to develop a list of potential biological pathways, genes and genetic variants involved in these quality-of-life outcomes, by

SUBMITTER: Sprangers MA 

PROVIDER: S-EPMC2824176 | biostudies-literature | 2009 Jun

REPOSITORIES: biostudies-literature