Model for end-stage liver disease score predicts left ventricular assist device operative transfusion requirements, morbidity, and mortality.

ABSTRACT:

Background

The Model for End-Stage Liver Disease (MELD) predicts events in cirrhotic subjects undergoing major surgery and may offer similar prognostication in left ventricular assist device candidates with comparable degrees of multisystem dysfunction.

Methods and results

Preoperative MELD scores were calculated for subjects enrolled in the University of Michigan Health System (UMHS) mechanical circulatory support database. Univariate and multiple regression analyses were performed to investigate the ability of patient characteristics, laboratory data (including MELD scores), and hemodynamic measurements to predict total perioperative blood product exposure and operative mortality. The ability of preoperative MELD scores to predict operative mortality was evaluated in subje

SUBMITTER: Matthews JC 

PROVIDER: S-EPMC2824259 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature