The synapsin gene family in basal chordates: evolutionary perspectives in metazoans.

ABSTRACT:

Background

Synapsins are neuronal phosphoproteins involved in several functions correlated with both neurotransmitter release and synaptogenesis. The comprehension of the basal role of the synapsin family is hampered in vertebrates by the existence of multiple synapsin genes. Therefore, studying homologous genes in basal chordates, devoid of genome duplication, could help to achieve a better understanding of the complex functions of these proteins.

Results

In this study we report the cloning and characterization of the Ciona intestinalis and amphioxus Branchiostoma floridae synapsin transcripts and the definition of their gene structure using available C. intestinalis and B. floridae genomic sequences. We demonstrate the occurrence, in both model organisms, of a single membe

SUBMITTER: Candiani S 

PROVIDER: S-EPMC2825198 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature