Is Helicobacter pylori associated with non-ulcer dyspepsia and will eradication improve symptoms? A meta-analysis.

ABSTRACT:

Objectives

To examine the association between Helicobacter pylori infection and non-ulcer dyspepsia, and to assess the effect of eradicating H pylori on dyspeptic symptoms in patients with non-ulcer dyspepsia.

Design

Systematic review and meta-analysis of (a) observational studies examining the association between Helicobacter pylori infection and non-ulcer dyspepsia (association studies), and (b) therapeutic trials examining the association between eradication of H pylori and dyspeptic symptoms in patients with non-ulcer dyspepsia (eradication trials).

Data sources

Randomised controlled trials and observational studies conducted worldwide and published between January 1983 and March 1999.

Main outcome measures

Summary odds ratios and summary symptom scores.

SUBMITTER: Jaakkimainen RL 

PROVIDER: S-EPMC28257 | biostudies-literature | 1999 Oct

REPOSITORIES: biostudies-literature