Bifrontal, bitemporal and right unilateral electrode placement in ECT: randomised trial.

ABSTRACT:

Background

Electroconvulsive therapy (ECT) is an effective treatment for major depression. Optimising efficacy and minimising cognitive impairment are goals of ongoing technical refinements.

Aims

To compare the efficacy and cognitive effects of a novel electrode placement, bifrontal, with two standard electrode placements, bitemporal and right unilateral in ECT.

Method

This multicentre randomised, double-blind, controlled trial (NCT00069407) was carried out from 2001 to 2006. A total of 230 individuals with major depression, bipolar and unipolar, were randomly assigned to one of three electrode placements during a course of ECT: bifrontal at one and a half times seizure threshold, bitemporal at one and a half times seizure threshold and right unilateral at six times s

SUBMITTER: Kellner CH 

PROVIDER: S-EPMC2830057 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature