Retrospective French nationwide survey of childhood aggressive vascular anomalies of bone, 1988-2009.

ABSTRACT:

Objective

To document the epidemiological, clinical, histological and radiological characteristics of aggressive vascular abnormalities of bone in children.

Study design

Correspondents of the French Society of Childhood Malignancies were asked to notify all cases of aggressive vascular abnormalities of bone diagnosed between January 1988 and September 2009.

Results

21 cases were identified; 62% of the patients were boys. No familial cases were observed, and the disease appeared to be sporadic. Mean age at diagnosis was 8.0 years [0.8-16.9 years]. Median follow-up was 3 years [0.3-17 years]. The main presenting signs were bone fracture (n = 4) and respiratory distress (n = 7), but more indolent onset was observed in 8 cases. Lung involvement, with lymphangiectasies and

SUBMITTER: Heritier S 

PROVIDER: S-EPMC2830950 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature