Genome-wide analysis of alternative splicing in Chlamydomonas reinhardtii.

ABSTRACT:

Background

Genome-wide computational analysis of alternative splicing (AS) in several flowering plants has revealed that pre-mRNAs from about 30% of genes undergo AS. Chlamydomonas, a simple unicellular green alga, is part of the lineage that includes land plants. However, it diverged from land plants about one billion years ago. Hence, it serves as a good model system to study alternative splicing in early photosynthetic eukaryotes, to obtain insights into the evolution of this process in plants, and to compare splicing in simple unicellular photosynthetic and non-photosynthetic eukaryotes. We performed a global analysis of alternative splicing in Chlamydomonas reinhardtii using its recently completed genome sequence and all available ESTs and cDNAs.

Results

Our analysis of

SUBMITTER: Labadorf A 

PROVIDER: S-EPMC2830987 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature