Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial.

ABSTRACT:

Context

The herbal product Ginkgo biloba is taken frequently with the intention of improving cognitive health in aging. However, evidence from adequately powered clinical trials is lacking regarding its effect on long-term cognitive functioning.

Objective

To determine whether G. biloba slows the rates of global or domain-specific cognitive decline in older adults.

Design, setting, and participants

The Ginkgo Evaluation of Memory (GEM) study, a randomized, double-blind, placebo-controlled clinical trial of 3069 community-dwelling participants aged 72 to 96 years, conducted in 6 academic medical centers in the United States between 2000 and 2008, with a median follow-up of 6.1 years.

Intervention

Twice-daily dose of 120-mg extract of G. biloba (n = 1545) or ident

SUBMITTER: Snitz BE 

PROVIDER: S-EPMC2832285 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature