Efficient production of 2-oxobutyrate from 2-hydroxybutyrate by using whole cells of Pseudomonas stutzeri strain SDM.

ABSTRACT: 2-Oxobutyrate is an important intermediate in the chemical, drug, and food industries. Whole cells of Pseudomonas stutzeri SDM, containing NAD-independent lactate dehydrogenases, effectively converted 2-hydroxybutyrate into 2-oxobutyrate. Under optimal conditions, the biocatalytic process produced 2-oxobutyrate at a high concentration (44.4 g liter(-1)) and a high yield (91.5%).

SUBMITTER: Gao C 

PROVIDER: S-EPMC2832366 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature