Modulation of motor behavior by dopamine and the D1-like dopamine receptor AmDOP2 in the honey bee.

ABSTRACT: Determining the specific molecular pathways through which dopamine affects behavior has been complicated by the presence of multiple dopamine receptor subtypes that couple to different second messenger pathways. The observation of freely moving adult bees in an arena was used to investigate the role of dopamine signaling in regulating the behavior of the honey bee. Dopamine or the dopamine receptor antagonist flupenthixol was injected into the hemolymph of worker honey bees. Significant differences between treated and control bees were seen for all behaviors (walking, stopped, upside down, grooming, flying and fanning), and behavioral shifts were dependent on drug dosage and time after injection. To examine the role of dopamine signaling through a specific dopamine receptor in the brain, R

SUBMITTER: Mustard JA 

PROVIDER: S-EPMC2834802 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature