Transcriptomic changes arising during light-induced sporulation in Physarum polycephalum.

ABSTRACT:

Background

Physarum polycephalum is a free-living amoebozoan protist displaying a complex life cycle, including alternation between single- and multinucleate stages through sporulation, a simple form of cell differentiation. Sporulation in Physarum can be experimentally induced by several external factors, and Physarum displays many biochemical features typical for metazoan cells, including metazoan-type signaling pathways, which makes this organism a model to study cell cycle, cell differentiation and cellular reprogramming.

Results

In order to identify the genes associated to the light-induced sporulation in Physarum, especially those related to signal transduction, we isolated RNA before and after photoinduction from sporulation- competent cells, and used these RNAs to sy

SUBMITTER: Barrantes I 

PROVIDER: S-EPMC2837032 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature