Defining species specific genome differences in malaria parasites.

ABSTRACT:

Background

In recent years a number of genome sequences for different plasmodium species have become available. This has allowed the identification of numerous conserved genes across the different species and has significantly enhanced our understanding of parasite biology. In contrast little is known about species specific differences between the different genomes partly due to the lower sequence coverage and therefore relatively poor annotation of some of the draft genomes particularly the rodent malarias parasite species.

Results

To improve the current annotation and gene identification status of the draft genomes of P. berghei, P. chabaudi and P. yoelii, we performed genome-wide comparisons between these three species. Through analyses via comparative genome hybridizatio

SUBMITTER: Liew KJ 

PROVIDER: S-EPMC2837034 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature