Genetic characterization of the influenza A pandemic (H1N1) 2009 virus isolates from India.

ABSTRACT:

Background

The Influenza A pandemic H1N1 2009 (H1N1pdm) virus appeared in India in May 2009 and thereafter outbreaks with considerable morbidity and mortality have been reported from many parts of the country. Continuous monitoring of the genetic makeup of the virus is essential to understand its evolution within the country in relation to global diversification and to track the mutations that may affect the behavior of the virus.

Methods

H1N1pdm viruses were isolated from both recovered and fatal cases representing major cities and sequenced. Phylogenetic analyses of six concatenated whole genomes and the hemagglutinin (HA) gene of seven more isolates from May-September 2009 was performed with reference to 685 whole genomes of global isolates available as of November 24, 20

SUBMITTER: Potdar VA 

PROVIDER: S-EPMC2837743 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature