Considerations for designing a prototype genetic test for use in translational research.

ABSTRACT:

Background

Translational research is needed to explore how people will respond to personal genetic susceptibility information related to common health conditions. Maximizing the rigor of this research will require that genetic test results be returned to study participants. Currently, there is no established method that guides the selection of genetic variants to be used in research with these objectives.

Methods and results

To address this question, we designed a process to identify gene variants and health conditions to be included in a prototype genetic test for use in a larger research effort, the Multiplex Initiative. The intention of this exploration was to facilitate research that generates individual genetic test results that are returned to study participants. Inclu

SUBMITTER: Wade CH 

PROVIDER: S-EPMC2837884 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature