Expanded multilocus sequence typing and comparative genomic hybridization of Campylobacter coli isolates from multiple hosts.

ABSTRACT: The purpose of this work was to evaluate the evolutionary history of Campylobacter coli isolates derived from multiple host sources and to use microarray comparative genomic hybridization to assess whether there are particular genes comprising the dispensable portion of the genome that are more commonly associated with certain host species. Genotyping and ClonalFrame analyses of an expanded 16-gene multilocus sequence typing (MLST) data set involving 85 isolates from 4 different hosts species tentatively supported the development of C. coli host-preferred groups and suggested that recombination has played various roles in their diversification; however, geography could not be excluded as a contributing factor underlying the history of some of the groups. Population genetic analyses of the

SUBMITTER: Lang P 

PROVIDER: S-EPMC2838017 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature