Baroreflex control of muscle sympathetic nerve activity: a nonpharmacological measure of baroreflex sensitivity.

ABSTRACT: The sensitivity of baroreflex control of sympathetic nerve activity (SNA) represents the responsiveness of SNA to changes in blood pressure. In a slightly different analysis, the baroreflex threshold measures the probability of whether a sympathetic burst will occur at a given diastolic blood pressure. We hypothesized that baroreflex threshold analysis could be used to estimate the sensitivity of the sympathetic baroreflex measured by the pharmacological modified Oxford test. We compared four measures of sympathetic baroreflex sensitivity in 25 young healthy participants: the "gold standard" modified Oxford analysis (nitroprusside and phenylephrine), nonbinned spontaneous baroreflex analysis, binned spontaneous baroreflex analysis, and threshold analysis. The latter three were performed du

SUBMITTER: Hart EC 

PROVIDER: S-EPMC2838548 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature