Deep brain stimulation for obsessive-compulsive disorder and treatment-resistant depression: systematic review.

ABSTRACT:

Background

In spite of advances in psychotherapy and pharmacotherapy, there are still a significant number of patients with depression and obsessive-compulsive disorder that are not aided by either intervention. Although still in the experimental stage, deep brain stimulation (DBS) offers many advantages over other physically-invasive procedures as a treatment for these psychiatric disorders. The purpose of this study is to systematically review reports on clinical trials of DBS for obsessive-compulsive disorder (OCD) and treatment-resistant depression (TRD). Locations for stimulation, success rates and effects of the stimulation on brain metabolism are noted when available. The first observation of the effects of DBS on OCD and TRD came in the course of using DBS to treat movement

SUBMITTER: Lakhan SE 

PROVIDER: S-EPMC2838907 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature