Ontology highlight
ABSTRACT:
SUBMITTER: Schadt EE
PROVIDER: S-EPMC2841396 | biostudies-literature | 2005 Jul
REPOSITORIES: biostudies-literature
Nature genetics 20050619 7
A key goal of biomedical research is to elucidate the complex network of gene interactions underlying complex traits such as common human diseases. Here we detail a multistep procedure for identifying potential key drivers of complex traits that integrates DNA-variation and gene-expression data with other complex trait data in segregating mouse populations. Ordering gene expression traits relative to one another and relative to other complex traits is achieved by systematically testing whether v ...[more]