Fatty acid extracts from Lucilia sericata larvae promote murine cutaneous wound healing by angiogenic activity.

ABSTRACT:

Background

fatty acids are considered to be effective components to promote wound healing and Lucilia sericata larvae are applied clinically to treat intractable wounds. We aimed to investigate the effect of fatty acid extracts from dried Lucilia sericata larvae on murine cutaneous wound healing as well as angiogenesis.

Results

On day 7 and 10 after murine acute excision wounds creation, the percent wound contraction of fatty acid extracts group was higher than that of vaseline group. On day 3, 7 and 10 after wounds creation, the wound healing quality of fatty acid extracts group was better than that of vaseline group on terms of granulation formation and collagen organization. On day 3 after wounds creation, the micro vessel density and vascular endothelial growth factor ex

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC2841600 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature