The complete genome sequence of Haloferax volcanii DS2, a model archaeon.

ABSTRACT:

Background

Haloferax volcanii is an easily culturable moderate halophile that grows on simple defined media, is readily transformable, and has a relatively stable genome. This, in combination with its biochemical and genetic tractability, has made Hfx. volcanii a key model organism, not only for the study of halophilicity, but also for archaeal biology in general.

Methodology/principal findings

We report here the sequencing and analysis of the genome of Hfx. volcanii DS2, the type strain of this species. The genome contains a main 2.848 Mb chromosome, three smaller chromosomes pHV1, 3, 4 (85, 438, 636 kb, respectively) and the pHV2 plasmid (6.4 kb).

Conclusions/significance

The completed genome sequence, presented here, provides an invaluable tool for further in vivo

SUBMITTER: Hartman AL 

PROVIDER: S-EPMC2841640 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature