Evaluation of oxidative stress biomarkers in patients with chronic renal failure: a case control study.

ABSTRACT:

Background

Oxidative stress is related to several diseases, including chronic renal insufficiency. The disequilibrium in the oxidant-antioxidant balance is the result of several metabolic changes. The majority of studies to-date have evaluated the grade of oxidative stress with a single biomarker, or a very limited number of them.

Findings

The present study used several important biomarkers to establish a score relating to oxidative stress status (glutathione S-transferase, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, reduced and oxidized glutathione, thiobarbituric acid reactive substances and hemolysis test). The score of oxidative stress (SOS) was then applied to a group of patients with renal insufficiency not on hemodialysis, and compar

SUBMITTER: Romeu M 

PROVIDER: S-EPMC2843731 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature