Abundant oligonucleotides common to most bacteria.

ABSTRACT:

Background

Bacteria show a bias in their genomic oligonucleotide composition far beyond that dictated by G+C content. Patterns of over- and underrepresented oligonucleotides carry a phylogenetic signal and are thus diagnostic for individual species. Patterns of short oligomers have been investigated by multiple groups in large numbers of bacteria genomes. However, global distributions of the most highly overrepresented mid-sized oligomers have not been assessed across all prokaryotes to date. We surveyed overrepresented mid-length oligomers across all prokaryotes and normalised for base composition and embedded oligomers using zero and second order Markov models.

Principal findings

Here we report a presumably ancient set of oligomers conserved and overrepresented in nearly a

SUBMITTER: Davenport CF 

PROVIDER: S-EPMC2843746 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature