Visceral Adiposity Index: a reliable indicator of visceral fat function associated with cardiometabolic risk.

ABSTRACT:

Objective

To individuate a novel sex-specific index, based on waist circumference, BMI, triglycerides, and HDL cholesterol, indirectly expressing visceral fat function.

Research design and methods

Visceral adiposity index (VAI) was first modeled on 315 nonobese healthy subjects. Using two multiple logistic regression models, VAI was retrospectively validated in 1,498 primary care patients in comparison to classical cardio- and cerebrovascular risk factors.

Results

All components of metabolic syndrome increased significantly across VAI quintiles. VAI was independently associated with both cardiovascular (odd ratio [OR] 2.45; 95% CI 1.52-3.95; P < 0.001) and cerebrovascular (1.63; 1.06-2.50; P = 0.025) events. VAI also showed significant inverse correlation with insulin

SUBMITTER: Amato MC 

PROVIDER: S-EPMC2845052 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature