Comparison of clinical and pathological staging in head and neck squamous cell carcinoma: results from Intergroup Study ECOG 4393/RTOG 9614.

ABSTRACT:

Objectives

To compare the results of clinical and pathological staging for a large cohort of patients with head and neck squamous cell carcinoma (HNSCC) and to examine patterns and ramifications of the disparity between staging methods.

Design

Prospective inception cohort (median follow-up, 7 years).

Setting

Multi-institutional cooperative group study (Eastern Cooperative Oncology Group 4393/Radiation Therapy Oncology Group 9614) involving 17 academic medical centers.

Patients

A total of 560 patients with new-onset or recurrent HNSCC enrolled during a 7-year period.

Interventions

Surgical resection with curative intent with or without adjuvant or previous radiotherapy or chemotherapy.

Main outcome measures

Clinical staging and pathological staging

SUBMITTER: Koch WM 

PROVIDER: S-EPMC2846171 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature