Computer-assisted quantitative evaluation of therapeutic responses for lymphoma using serial PET/CT imaging.

ABSTRACT:

Rationale and objectives

Molecular imaging modalities such as positron emission tomography (PET)/computed tomography (CT) have emerged as an essential diagnostic tool for monitoring treatment response in lymphoma patients. However, quantitative assessment of treatment outcomes from serial scans is often difficult, laborious, and time consuming. Automatic quantization of longitudinal PET/CT scans provides more efficient and comprehensive quantitative evaluation of cancer therapeutic responses. This study develops and validates a Longitudinal Image Navigation and Analysis (LINA) system for this quantitative imaging application.

Materials and methods

LINA is designed to automatically construct longitudinal correspondence along serial images of individual patients for changes in

SUBMITTER: Gao X 

PROVIDER: S-EPMC2846835 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature