Development of a SNP resource and a genetic linkage map for Atlantic cod (Gadus morhua).

ABSTRACT:

Background

Atlantic cod (Gadus morhua) is a species with increasing economic significance for the aquaculture industry. The genetic improvement of cod will play a critical role in achieving successful large-scale aquaculture. While many microsatellite markers have been developed in cod, the number of single nucleotide polymorphisms (SNPs) is currently limited. Here we report the identification of SNPs from sequence data generated by a large-scale expressed sequence tag (EST) program, focusing on fish originating from Canadian waters.

Results

A total of 97976 ESTs were assembled to generate 13448 contigs. We detected 4753 SNPs that met our selection criteria (depth of coverage > or = 4 reads; minor allele frequency > 25%). 3072 SNPs were selected for testing. The percentage o

SUBMITTER: Hubert S 

PROVIDER: S-EPMC2846918 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature