Large-scale transcriptome data reveals transcriptional activity of fission yeast LTR retrotransposons.

ABSTRACT:

Background

Retrotransposons are transposable elements that proliferate within eukaryotic genomes through a process involving reverse transcription. The numbers of retrotransposons within genomes and differences between closely related species may yield insight into the evolutionary history of the elements. Less is known about the ongoing dynamics of retrotransposons, as analysis of genome sequences will only reveal insertions of retrotransposons that are fixed--or near fixation--in the population or strain from which genetic material has been extracted for sequencing. One pre-requisite for retrotransposition is transcription of the elements. Given their intrinsic sequence redundancy, transcriptome-level analyses of transposable elements are scarce. We have used recently published t

SUBMITTER: Mourier T 

PROVIDER: S-EPMC2848245 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature