Meredys, a multi-compartment reaction-diffusion simulator using multistate realistic molecular complexes.

ABSTRACT:

Background

Most cellular signal transduction mechanisms depend on a few molecular partners whose roles depend on their position and movement in relation to the input signal. This movement can follow various rules and take place in different compartments. Additionally, the molecules can form transient complexes. Complexation and signal transduction depend on the specific states partners and complexes adopt. Several spatial simulator have been developed to date, but none are able to model reaction-diffusion of realistic multi-state transient complexes.

Results

Meredys allows for the simulation of multi-component, multi-feature state molecular species in two and three dimensions. Several compartments can be defined with different diffusion and boundary properties. The software

SUBMITTER: Tolle DP 

PROVIDER: S-EPMC2848630 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature