Rapid diagnosis of azole-resistant aspergillosis by direct PCR using tissue specimens.

ABSTRACT: We report the use of PCR techniques on a formalin-fixed and paraffin-embedded tissue specimen for direct detection of one dominant azole resistance mechanism in a case of disseminated invasive aspergillosis. Rapid detection of mutations associated with azole resistance directly in tissue significantly reduces diagnostic delay.

SUBMITTER: van der Linden JW 

PROVIDER: S-EPMC2849623 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature