Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: a systematic review of randomised trials.

ABSTRACT:

Objective

To determine the effect on mortality of rescuscitation with colloid solutions compared with resuscitation with crystalloids.

Design

Systematic review of randomised controlled trials of resuscitation with colloids compared with crystalloids for volume replacement of critically ill patients; analysis stratified according to patient type and quality of allocation concealment.

Subjects

37 randomised controlled trials were eligible, of which 26 unconfounded trials compared colloids with crystalloids (n = 1622). (The 10 trials that compared colloid in hypertonic crystalloid with isotonic crystalloid (n = 1422) and one trial that compared colloid in isotonic crystalloid with hypertonic crystalloid (n = 38) are described in the longer version on our website www.bmj.

SUBMITTER: Schierhout G 

PROVIDER: S-EPMC28497 | biostudies-literature | 1998 Mar

REPOSITORIES: biostudies-literature