CoBaltDB: Complete bacterial and archaeal orfeomes subcellular localization database and associated resources.

ABSTRACT:

Background

The functions of proteins are strongly related to their localization in cell compartments (for example the cytoplasm or membranes) but the experimental determination of the sub-cellular localization of proteomes is laborious and expensive. A fast and low-cost alternative approach is in silico prediction, based on features of the protein primary sequences. However, biologists are confronted with a very large number of computational tools that use different methods that address various localization features with diverse specificities and sensitivities. As a result, exploiting these computer resources to predict protein localization accurately involves querying all tools and comparing every prediction output; this is a painstaking task. Therefore, we developed a comprehensi

SUBMITTER: Goudenege D 

PROVIDER: S-EPMC2850352 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature