Analysis of the genome content of Lactococcus garvieae by genomic interspecies microarray hybridization.

ABSTRACT:

Background

Lactococcus garvieae is a bacterial pathogen that affects different animal species in addition to humans. Despite the widespread distribution and emerging clinical significance of L. garvieae in both veterinary and human medicine, there is almost a complete lack of knowledge about the genetic content of this microorganism. In the present study, the genomic content of L. garvieae CECT 4531 was analysed using bioinformatics tools and microarray-based comparative genomic hybridization (CGH) experiments. Lactococcus lactis subsp. lactis IL1403 and Streptococcus pneumoniae TIGR4 were used as reference microorganisms.

Results

The combination and integration of in silico analyses and in vitro CGH experiments, performed in comparison with the reference microorganisms, all

SUBMITTER: Aguado-Urda M 

PROVIDER: S-EPMC2851595 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature