Randomised controlled trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease: the POPI (prevention of pelvic infection) trial.

ABSTRACT:

Objective

To determine whether screening and treating women for chlamydial infection reduces the incidence of pelvic inflammatory disease over the subsequent 12 months.

Design

Randomised controlled trial.

Setting

Common rooms, lecture theatres, and student bars at universities and further education colleges in London.

Participants

2529 sexually active female students, mean age 21 years (range 16-27).

Intervention

Participants completed a questionnaire and provided self taken vaginal swabs, with follow-up after one year. Samples were randomly allocated to immediate testing and treatment for chlamydial infection, or storage and analysis after a year (deferred screening controls).

Main outcome measure

Incidence of clinical pelvic inflammatory disease

SUBMITTER: Oakeshott P 

PROVIDER: S-EPMC2851939 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature