Antimicrobial peptide-like genes in Nasonia vitripennis: a genomic perspective.

ABSTRACT:

Background

Antimicrobial peptides (AMPs) are an essential component of innate immunity which can rapidly respond to diverse microbial pathogens. Insects, as a rich source of AMPs, attract great attention of scientists in both understanding of the basic biology of the immune system and searching molecular templates for anti-infective drug design. Despite a large number of AMPs have been identified from different insect species, little information in terms of these peptides is available from parasitic insects.

Results

By using integrated computational approaches to systemically mining the Hymenopteran parasitic wasp Nasonia vitripennis genome, we establish the first AMP repertoire whose members exhibit extensive sequence and structural diversity and can be distinguished into m

SUBMITTER: Tian C 

PROVIDER: S-EPMC2853521 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature