Plasma adipokines, bone mass, and hip geometry in rural Chinese adolescents.

ABSTRACT:

Context

Adipokines have been linked to bone phenotypes recently, but with conflicting results. Few such studies have been conducted in adolescents.

Objective

The aim of the study was to examine the associations of adiponectin and leptin with multiple bone phenotypes in Chinese adolescents and estimate the genetic contribution to these associations.

Design and setting

This was a cross-sectional study conducted in rural China.

Participants

A total of 675 males and 575 females aged 13-21 yr were included.

Outcome measures

Fat mass (FM), lean mass (LM), bone area (BA), bone mineral content (BMC), cross-sectional area (CSA), and section modulus (SM) were measured by dual-energy x-ray absorptiometry. Plasma adipokine concentration was determined using sandwich

SUBMITTER: Hong X 

PROVIDER: S-EPMC2853982 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature