Enamine-iminium ion Nazarov cyclization of alpha-ketoenones.

ABSTRACT: The mono-triflate salts of some chiral nonracemic 1,2-diamines react with alpha-ketoenones in a stoichiometric reaction to form products of the Nazarov cyclization in high enantiomeric ratios. The mechanism appears to involve rearrangement of an enamine-iminium ion.

SUBMITTER: Bow WF 

PROVIDER: S-EPMC2854558 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature