Distinct pathways mediate the sorting of tail-anchored proteins to the plastid outer envelope.

ABSTRACT:

Background

Tail-anchored (TA) proteins are a distinct class of membrane proteins that are sorted post-translationally to various organelles and function in a number of important cellular processes, including redox reactions, vesicular trafficking and protein translocation. While the molecular targeting signals and pathways responsible for sorting TA proteins to their correct intracellular destinations in yeasts and mammals have begun to be characterized, relatively little is known about TA protein biogenesis in plant cells, especially for those sorted to the plastid outer envelope.

Methodology/principal findings

Here we investigated the biogenesis of three plastid TA proteins, including the 33-kDa and 34-kDa GTPases of the translocon at the outer envelope of chloroplasts (To

SUBMITTER: Dhanoa PK 

PROVIDER: S-EPMC2854689 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature