Serum n-6 fatty acids and lipoprotein subclasses in middle-aged men: the population-based cross-sectional ERA-JUMP study.

ABSTRACT:

Background

The associations of serum omega-6 (n-6) fatty acids with lipoprotein subclasses at the population level are uncertain.

Objective

We aimed to examine associations between major n-6 fatty acids [ie, linoleic acid (LA, 18:2n-6) and arachidonic acid (AA, 20:4n-6)] and the lipoprotein subclasses VLDL, LDL, and HDL.

Design

We conducted a cross-sectional study in 1098 participants using population-based data from US white, Japanese American, Japanese, and Korean men aged 40-49 y. Serum fatty acids were analyzed by capillary gas-liquid chromatography. Lipoprotein subclasses were measured by nuclear magnetic resonance spectroscopy. Multiple linear regression models as a function of each fatty acid were used after adjustment for age, population, body mass index, pack

SUBMITTER: Choo J 

PROVIDER: S-EPMC2854899 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature