Right dorsolateral prefrontal cortical activity and behavioral inhibition.

ABSTRACT: Individuals show marked variation in their responses to threat. Such individual differences in behavioral inhibition play a profound role in mental and physical well-being. Behavioral inhibition is thought to reflect variation in the sensitivity of a distributed neural system responsible for generating anxiety and organizing defensive responses to threat and punishment. Although progress has been made in identifying the key constituents of this behavioral inhibition system in humans, the involvement of dorsolateral prefrontal cortex (DLPFC) remains unclear. Here, we acquired self-reported Behavioral Inhibition System Sensitivity scores and high-resolution electroencephalography from a large sample (n= 51). Using the enhanced spatial resolution afforded by source modeling techniques, we sho

SUBMITTER: Shackman AJ 

PROVIDER: S-EPMC2858783 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature