Asymmetric rostro-caudal inhibition in the primary olfactory cortex.

ABSTRACT: The importance of intracortical inhibitory circuits in setting the feature-selective spatial organization of primary sensory cortices remains controversial. To address this issue, we examined the strength of interneuron-to-pyramidal cell connections across the rat anterior piriform cortex (aPC) and found a pronounced gradient of increasing pyramidal cell inhibition along the aPC rostro-caudal axis. This functional heterogeneity could govern aPC spatial activation in response to varying odor identities and features.

SUBMITTER: Luna VM 

PROVIDER: S-EPMC2860678 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature