Appetitive hormones, but not isoflavone tablets, influence overall and central adiposity in healthy postmenopausal women.

ABSTRACT:

Objective

One of the multiple health benefits of soy protein or its isoflavones may be their purported favorable effect on body composition. We examined the effect of isoflavones extracted from soy protein on overall and regional body composition, taking into account appetitive hormones as potential mediators, as well as the direct effect on appetitive hormones.

Methods

This randomized, double-blind, placebo-controlled multicenter trial included 229 healthy postmenopausal women (age, 45.8-65 y; body mass index, 24.9 +/- 3.0 kg/m) who consumed placebo or soy isoflavone (80 or 120 mg/d) tablets for 12 months. We used intent-to-treat analysis to examine changes in body composition (whole-body lean mass, whole-body fat mass, androidal fat mass, and androidal-to-gynoidal fat mass

SUBMITTER: Matvienko OA 

PROVIDER: S-EPMC2866788 | biostudies-literature | 2010 May-Jun

REPOSITORIES: biostudies-literature