Synthesis and evaluation of a series of C5'-substituted duocarmycin SA analogs.

ABSTRACT: The synthesis and evaluation of a key series of analogs of duocarmycin SA, bearing a single substituent at the C5' position of the DNA binding subunit, are described.

SUBMITTER: Robertson WM 

PROVIDER: S-EPMC2867475 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature