Surveillance and simulation of bovine spongiform encephalopathy and scrapie in small ruminants in Switzerland.

ABSTRACT:

Background

After bovine spongiform encephalopathy (BSE) emerged in European cattle livestock in 1986 a fundamental question was whether the agent established also in the small ruminants' population. In Switzerland transmissible spongiform encephalopathies (TSEs) in small ruminants have been monitored since 1990. While in the most recent TSE cases a BSE infection could be excluded, for historical cases techniques to discriminate scrapie from BSE had not been available at the time of diagnosis and thus their status remained unclear. We herein applied state-of-the-art techniques to retrospectively classify these animals and to re-analyze the affected flocks for secondary cases. These results were the basis for models, simulating the course of TSEs over a period of 70 years. The aim wa

SUBMITTER: Hausermann C 

PROVIDER: S-EPMC2867968 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature