Acute encephalopathy associated with influenza A infection in adults.

ABSTRACT: We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios > or =3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis.

SUBMITTER: Lee N 

PROVIDER: S-EPMC2874350 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature