Isolation and characterization of a virulent bacteriophage AB1 of Acinetobacter baumannii.

ABSTRACT:

Background

Acinetobacter baumannii is an emerging nosocomial pathogen worldwide with increasing prevalence of multi-drug and pan-drug resistance. A. baumannii exists widely in natural environment, especially in health care settings, and has been shown difficult to be eradicated. Bacteriophages are often considered alternative agent for controlling bacterial infection and contamination. In this study, we described the isolation and characterization of one virulent bacteriophage AB1 capable of specifically infecting A. baumannii.

Results

A virulent bacteriophage AB1, specific for infecting a clinical strain A. baumannii KD311, was first isolated from marine sediment sample. Restriction analysis indicated that phage AB1 was a dsDNA virus with an approximate genome size of 45.2

SUBMITTER: Yang H 

PROVIDER: S-EPMC2874798 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature